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Metformin Archives - Public Safety & Vigilance

Decreased vitamin B12 levels with metformin use: MHRA Drug Safety Update

MHRA released a safety update for Metformin product related to the new adverse drug reaction- Vitamin B12 Deficiency. Based on the recent review of safety data from brand leader Glucophage (metformin) from the Europe, it was identified that vitamin B12 deficiency is a common adverse drug reaction which may affect up to 1 in 10

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